Management of patients with refractory migraine and PFO: Is MIST I relevant?

Authors
Category Primary study
JournalCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Year 2008
The results of the randomized clinical trial entitled: Migraine Intervention with Starflex Technology (MIST), produced surprising and disappointing results on the effect of PFO closure to decrease migraine headaches. There have been allegations of misrepresentation of the effectiveness of this device. These issues have significant implications in how randomized clinical trials are performed that will impact current and future planned trials of PFO closure to treat migraine headaches.
Epistemonikos ID: 6821a8a9a031e4d43d7ab78d1a0b4b703d41244d
First added on: Aug 31, 2023