Short-term exercise training and its effect on glucose tolerance and immune function

INTERVENTION: Participants will be randomised into an exercise group of either treadmill or cycle exercise. Exercise will last for 45 minutes (moderate intensity at 65% of VO2peak) and will last for 10 sessions over a two‐week period at the Murdoch University exercise physiology laboratory. An oral glucose tolerance test will be completed pre and post‐training with blood samples taken every 30 minutes. Blood samples will also be used to measure immune related cells such as regulatory T cells. Familiarisation will preceed training with a VO2peak test, body composition analysis and anthropometrics measured. Exercise will be supervised by the PhD student who is running the project. CONDITION: Type 2 diabetes PRIMARY OUTCOME: Glucose tolerance via oral glucose tolerance test (75g glucose). ; Participants will ingest a 75g‐carbohydrate containing drink in a fasted state. SECONDARY OUTCOME: Regulatory T cells will be assessed via flow cytometry from whole blood samples collected prior to the ingestion of the oral glucose tolerance test. INCLUSION CRITERIA: Diagnosed as type 2 diabetic, BMI > 27 Sedentary or low level of physical activity (1 or 2 bouts per week)