Effect of percutaneous acupoint electrical stimulation on improving postoperative neurocognitive impairment and its anti-inflammatory mechanism

INTERVENTION: Test group:Percutaneous acupoint electrical stimulation;Control group:Only the electrodes were attached to the corresponding acupoints, but the pulse therapeutic apparatus was not connected; CONDITION: perioperative neurocognitive disorders PRIMARY OUTCOME: Mini‐mental State Examination;Wechsler Adult Intelli‐gence Scale‐Fourth Edition; SECONDARY OUTCOME: malondialdehyde;Superoxide dismutase;umor necrosis factor alpha;Interleukin 1ß;Interleukin 6;Interleukin‐10;euron specific enolase;Serum S‐100ß protein; INCLUSION CRITERIA: 1) Open surgery lasting =2 h; 2) Age 65‐85; 3) Postoperative hospital stay =7 days; 4) ASA was graded ?‐?.