A study for evaluating the effects of the intake of cocoa on bowel movement and fecal malodor. A placebo-controlled crossover trial

INTERVENTION: Intake of a drink containing cocoa for 2 weeks, wash out for 2 weeks, Intake of a drink without cocoa for 2 weeks Intake of a drink without cocoa for 2 weeks, wash out for 2 weeks, Intake of a drink containing cocoa for 2 weeks CONDITION: Subjects with a tendency for constipation PRIMARY OUTCOME: Defecation frequency, fecal amount, fecal odor SECONDARY OUTCOME: Fecal conditions(fecal hardness, fecal color, fecal shape, feeling after defecation), fecal ammonia content, fecal putrefaction products content(indole, skatol) INCLUSION CRITERIA: (1)Males and females from 20 to 60 years old (2)Subjects with a tendency for constipation at two to five times defecation per week (3)Healthy subjects with not taking any medicine (4)Subjects who can keep their stools in freeze immediately after defecation (5)Obtaining informed consent and signed a consent form