A clinical trial to Study the effects of oral tofacitinib and azathioprine in chronic actinic dermatitis

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2023
INTERVENTION: Intervention1: Tablet Tofacitinib: Group B (18 patients) will be given Tablet Tofacitinib 5mg twice daily orally for 3months.The first and second follow up will be conducted after 15 days and 30 days respectively, followed by once monthly visits, making a total of 4 follow up visits for each patient. Control Intervention1: Tablet Azathioprine: Group A (18 patients) will be given tablet Azathioprine 100mg once daily orally for 3months.The first and second follow up will be after 15 and 30 days respectively, followed by once monthly visits, making a total of 4 follow up visits for each patient. CONDITION: Health Condition 1: L562‐ Photocontact dermatitis [berloquedermatitis] PRIMARY OUTCOME: To compare the efficacy and safety of oral tofacitinib with azathioprine in chronic actinic dermatitisTimepoint: At baseline,15 days,30 days,2 months and 3 months. SECONDARY OUTCOME: Not applicableTimepoint: Not applicable INCLUSION CRITERIA: 1. Patients with Clinical diagnosis of chronic actinic dermatitis including: Actinic Prurigo Actinic cheilitis Lichenoid photodermatitis Photoallergic dermatitis Phytophotodermatitis Actinic reticuloid 2. Age group more than 18 years of age. 3. The patient should have given written consent before the investigations and starting the drug. 4. The patient should be able and willing and fit, in the view of the investigator, to comply with all study procedures
Epistemonikos ID: 65455ce656b145b6979ae462e11e53f257b1245a
First added on: Feb 20, 2024