Effect of Reinforcing Kidney,Nourishing and Activating Blood Combined with In Vitro Fertilization-Embryo Transplantation on Pregnancy Rate

OBJECTIVE: To observe the effect of the reinforcing kidney,nourishing and activating blood on promoting ovulation and improving the endometrium thickness and pregnancy rate in the process of in vitro fertilization-embryo transplantation(IVF-ET). METHODS: The 63 cases receiving IVF-ET were randomly divided into two groups: the treatment group(n=31) treated with GnRHa/r-FSH/HMG/HCG combined with the herbs of kidney-reinforcing,blood-nourishing and blood-activating in different periods of IVF-ET,and the control group(n=32) with GnRHa/ r-FSH/HMG/HCG alone.The dose of gonadotropin(Gn),endometrium thickness,follicular oocyte number,high-quality oocyte rate,fertilization rate,high-quality embryo rate and pregnancy rate of both groups were observed. RESULTS: In the treatment group,Gn dose was significantly lower(P0.01) and endometrium thickness increased(P0.05),and the effect on increasing the high-quality oocyte rate,fertilization rate,high-quality embryo rate,and pregnancy rate was better than that in the control group(P0.05). CONCLUSION: The therapy of replenishing kidney,nourishing and activating blood is effective in promoting ovulation,increasing endometrium thickness,and helping embryo implantation.In combination with IVF-ET,it increases the pregnancy rate,serving as an effective treatment for infertile women.