Use of tansagem, as a mouthwash, in cancer-related lesions

Authors
Category Primary study
Registry of TrialsBrazilian Registry of Clinical Trials
Year 2024
INTERVENTION: To formulate and evaluate the effects of a mouthwash with Plantago major L. extract (tansage) applied as a mouthwash in patients with chemotherapy‐induced mucositis. The intervention took place through a randomized, double‐blind clinical study in an Oncology clinic in the Southwest of PR, where patients who were undergoing chemotherapy presented oral lesions due to the use of chemotherapy. All patients were evaluated at the specific time of the study and analyzed. together with the dentist what degree of mucositis they had. Patients who had some degree of mucositis were selected. In the end, 11 patients were recruited, divided into two groups (control) using chlorhexidine‐based mouthwash and (intervention) using tansy‐based mouthwash, statistical analyzes (Student T test and p value) were evaluated regarding the pain level and degree of oral mucositis. The patient's initial assessment took place on days 0, 7 and 14. CONDITION: Oral Mucositis; Drug‐Related Side Effects and Adverse Reactions PRIMARY OUTCOME: Expected outcome 1: It is expected to improve the quality of life of patients with oral mucositis induced by chemotherapy and radiotherapy during cancer treatment, using a mouthwash based on Plantago major L extract SECONDARY OUTCOME: No secondary outcomes are expected INCLUSION CRITERIA: Male and/or female patients diagnosed with cancer undergoing chemotherapy; over 18 years old; who have some degree of mucositis according to the World Health Organization
Epistemonikos ID: 6401925d3cddea72c5d45ab07757ac733984a897
First added on: Aug 28, 2024