Effects of Irrigation Activation and Obturation Techniques on Pain After Root Canal Treatment

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This randomized controlled clinical trial aimed to compare postoperative pain and analgesic use following single-visit root canal treatment performed using different final irrigation activation and root canal obturation techniques in patients with symptomatic irreversible pulpitis. A total of 72 adult patients aged 18 to 65 years with symptomatic irreversible pulpitis in permanent single rooted, single canal teeth were randomly assigned to four treatment groups (18 patients in each group). The groups received conventional needle irrigation with cold lateral condensation, EDDY sonic irrigation activation with cold lateral condensation, conventional needle irrigation with Fast-Fill thermoplasticized obturation, or EDDY sonic irrigation activation with Fast-Fill thermoplasticized obturation. All treatments were completed in a single visit using standardized root canal preparation procedures. Pain intensity was recorded using a 0-10 Numerical Rating Scale before treatment and at 8, 24, and 48 hours and 7 days after treatment. The use of pain-relieving medication was also recorded. The study was designed to determine whether irrigation activation and obturation techniques influence postoperative pain and analgesic consumption following root canal treatment.
Epistemonikos ID: 63750e276feafd74f3b2e7a33337077062c073a2
First added on: Oct 21, 2026