Drug-drug Interactions Between DZD9008 and Itraconazole/Carbamazepine

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2022
This is a Phase 1, single-center, nonrandomized, open-label, 2-part, fixed-sequence, drug-drug interaction (DDI) study to assess the effect of multiple doses of itraconazole, a CYP3A4 enzyme inhibitor, on the single dose PK of DZD9008 in healthy adult subjects (Part A) and to assess the effect of multiple doses of carbamazepine, a CYP3A4 inducer, on the single dose PK of DZD9008 in healthy adult subjects (Part B).
Epistemonikos ID: 62cec6f75a3741edbcbe0710f951ec54f2276bfc
First added on: Oct 02, 2023