Evaluation and Meta Analysis of Needle Medicine in Treatment of Peripheral Neuropathy in Diabetes

Objective: Systematic evaluation of clinical efficacy of needle drugs combined with treatment of peripheral neuropathy in diabetes Method: Computer retrieval of CNKI, WANFANG, VIP, PubMed, etc. The time limit for retrieval is up to November 2017. According to the criteria for inclusion and exclusion, literature screening and extraction are conducted independently by 2 evaluators and information extraction. The quality of the dedication was evaluated after using the Rev Man 5.3 Software conducted Meta analysis. Results: Inclusion of 2277 patients in 24 clinical randomized controlled trials, Meta analysis showed that the total effective efficiency of acupuncture combined with drugs to treat diabetes (observation group) was higher than the conventional drug therapy group (control group), the inefficiency was lower than the control group, the difference was statistically significant significance (P≈ 0.05); the effectiveness of observation groups and control groups is comparable , the difference is not statistically significant (P. 0.05). Conclusion: Needle drugs are safe and effective in treating peripheral neuropathy in diabetes, but because of the low volume and low quality of the literature, further confirmed by a large sample and high-quality randomized controlled trial.