The Role of male sex hormone in Angiogenesis and Endothelial Progenitor Cell Mobilisation

Authors
Category Primary study
Registry of TrialsANZCTR
Year 2010
INTERVENTION: Primoteston (testosterone enanthate) 250mg intramuscular injection weekly for 6 weeks CONDITION: effect of androgen on formation of new blood vessels PRIMARY OUTCOME: endothelial progenitor cell functions assessment after treatment using in vitro assay (Asahara stain, Boyden chamber, and tubulogenesis assay), and in vivo model (cells transplanted to mice) SECONDARY OUTCOME: effect on flow‐mediated dilatation (FMD) of brachial artery using ultrasound INCLUSION CRITERIA: all males, except for those aged 35‐55 years old, and 18 is the minimum age
Epistemonikos ID: 60f475fa681ed81f71cdd1b02c9de83170709003
First added on: Aug 25, 2024