Pediatric COVID-19 in Southern California: clinical features and viral genetic diversity

Category Primary study
Pre-printmedRxiv
Year 2020
Links DOI , medRxiv
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As the pandemic enters its fifth month, information regarding COVID-19 in children is rapidly evolving. Here, we explore clinical features and SARS-CoV-2 genetic variation in children presenting with COVID-19. We observed diverse clinical presentations and identified association between disease severity, viral load and age. SARS-CoV-2 genomes from the patients showed limited number of variations and an evolutionary rate comparable to other RNA viruses. We did not identify correlation between disease severity and viral genetic variations. Epidemiological investigation revealed multiple introductions of virus into Southern California.
The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license
Epistemonikos ID: 60c78c4902800354c8a1409fc5ff5c58977fce6d
First added on: Jun 01, 2020