A study comparing etomidate and ketofol two anaesthesia drugs for maintaining stable heart rate and blood pressure during airway tube placement that is blockbuster airway device in adult patients having scheduled surgeries

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Intravenous ketofol: Patients will receive intravenous ketofol that is equal mixture of ketamine and propofol administered slowly over 30 to 60 seconds during induction of anaesthesia Control Intervention1: Intravenous etomidate: Patients will receive intravenous etomidate 0.3 mg per kg administered slowly over 30 to 60 seconds during induction of anaesthesia CONDITION: Health Condition 1: 3‐ Administration PRIMARY OUTCOME: Hemodynamic parameters, including Heart Rate and Mean Arterial Pressure, SBP, DBP, SPO2 and EtCO2 will be recordedTimepoint: immediately after induction of anaesthesia, at time of insertion of Blockbuster Supraglottic Airway Device, after 1 minute of insertion, 3 minutes after insertion, 5 minutes after insertion and after 10 minutes of insertion of Blockbuster Supraglottic Airway Device. ; SECONDARY OUTCOME: Any adverse airway events during this phase such as desaturation that is SpO2 less than 90 percent, laryngospasm, ECG changes and sore throat will be documentedTimepoint: from reaching of patient from OT to Post Anesthesia Care Unit that is PACU and after every 5 minutes till first 15 minutes. ; ; INCLUSION CRITERIA: Patients in age group of 18 to 60 years American Society of Anaesthesiologists Status 1 and 2
Epistemonikos ID: 5f3ffc4eefeb0f7f4d1b87fb9d8a96f09c6c7eb3
First added on: Oct 08, 2026