The Influence of Tramadol on Opioid-induced Bowel Dysfunction

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2022
Tramadol is a weak opioid and widely used to treat moderate to severe pain. Stronger opioids are known to inhibit gastrointestinal motility and secretion, however the effects of tramadol on gastrointestinal function remains less understood. The aim of this study was to determine to what degree tramadol causes opioid-induced bowel dysfunction by using an objective design to explore gastrointestinal transit, motility pattern, secretion, and colonic volume, in a group of healthy male volunteers.
Epistemonikos ID: 5e0b7994dfa12d89248860bd4d1493bf0e6e3477
First added on: May 16, 2024