CODEPAD-III (Collaborative Outcomes of DEpression and Pain Associated With Delivery-III)

Postnatal depression (PND) represents a substantial burden, contributing to adverseoutcomes for mothers, their infants, and families. The global incidence of PND has beenreported to be about 17%, with Southeast Asia countries having a pooled incidence of 22%.Established risk factors include the severity of pain experienced during childbirth,analgesic techniques employed, and underlying psychological vulnerabilities.Cesarean delivery, especially emergency Cesarean delivery, has been associated with anincreased risk of PND. Childbirth often results in substantial tissue trauma, which maylead to persistent postpartum pain (PPP) that affects up to 20% of women globally. BothPND and PPP could contribute to a significant socioeconomic burden and diminished qualityof life. Non‐pharmacological interventions have demonstrated effectiveness in reducingdepression and pain in postpartum women, as well as in populations with depression, andchronic pain. However, it remains uncertain whether delivering these interventions aspart of a structured Collaborative Psychological Model (CPM) can effectively reduce theincidence of both PND and PPP. Currently, there is a lack of standardized and effectiveprograms, with high risk PND stratification, addressing these outcomes in routineclinical care.The proposed CPM in this study addresses these gaps through electronic surveys and mobileapps that enable mothers to manage their mental health without reliance onpharmacological therapy in a comfortable and private manner. By integrating multipleevidence‐based interventions into a single program, we aim to leverage upon theirindividual efficacies and achieve a synergistic effect to improve outcomes related to PNDand PPP.