Bleeding Control after Tooth Removal in a patient using anticoagulant medication

INTERVENTION: G09.188.390 This is a randomized clinical trial with 2 arms, based on the CONSORT protocol. The researcher responsible for randomization will not have access to the recruitment of individuals and the researcher who will evaluate the outcome, as well as the participant, will only know which group they belong to immediately after tooth extraction, when the envelope with the type of treatment selected will be opened . A total of 62 subjects who meet the eligibility criteria will be allocated to either intervention group. Experimental group 1: 31 individuals will receive L‐PRF (platelet aggregate) in the socket after extraction and the other 31 individuals will belong to experimental group 2 in which they will receive hemospon in the socket. The surgeon in charge will evaluate the alveoli in the postoperative period, applying the subjective assessment referring to the level of bleeding, in which the patient must remain under rest for 30 minutes after the procedure to verify the bleeding status of all operated sites, the then it should be reassessed at the bedside after 2h, 6h, 1 day and 7 days postoperatively, when the suture is removed. CONDITION: A12.207.270.695.600.500 Oral Surgical Procedures; Anticoagulants PRIMARY OUTCOME: Hemostasis is expected in the immediate postoperative period, in the first 24 hours after surgery. SECONDARY OUTCOME: It is expected to find the presence of mediate postoperative bleeding (yes or no), from the 2nd to the 7th postoperative day INCLUSION CRITERIA: Volunteers using anticoagulant therapy continuously; with Surgical indication for tooth extraction; with international normalized ratio (INR) values reported by prothrombin time of up to 3.5; who agree to participate in the research and sign the term of free and informed consent (TCLE) specific to the research in question