Chronomodulated chemotherapy versus conventional chemotherapy for advanced colorectal cancer: a meta-analysis of five randomized controlled trials

Authors
Category Structured summary of systematic reviews
JournalDatabase of Abstracts of Reviews of Effects (DARE)
Year 2010
CRD SUMMARY: The review found the chronomodulated chemotherapy was more effective than conventional chemotherapy in improving overall survival in patients with advanced colorectal cancer without substantially increasing side effects. The authors' conclusions reflected the evidence base, but in light of shortcomings in the reporting of the review and the quality of the included trials, the authors' conclusions should be interpreted with caution.
Epistemonikos ID: 5bde74c6ba5bfb2175358f9570cb530a2ac990ce
First added on: Jan 04, 2012