Improve Immunity Through the Physical Exercise to Heart Patients

INTERVENTION: Behavioural D010806 D015444 Forty patients were randomized by drawing randomly and proportionally between the two arms of the study, characterized as aerobic exercise of moderate and high intensity. However, the patient was masked as to identify the group to which he belongs was, because it was only informed heart rate stipulated by cardiopulmonary exercise testing, exercise intensity corresponding to which the same would hold, not being informed at the same if this was moderate or high intensity. All patients underwent the same type of aerobic exercise on a treadmill for 12 weeks, with a frequency of 3 times per week, in which differed by the intensity, and then divided into: Control Group (n = 20): continuous aerobic training of moderate intensity, 75% of Heart Rate stipulated by cardiopulmonary exercise test, lasting 40 minutes. Intervention group (n = 20): High Intensity Interval Training, sustaining the greatest time to 92% Heart Rate stipulated by cardiopulmonary exercise test, using 2‐3 minutes of active rest at 75% Heart Rate, characterizing the interval workout, 40 minutes. In addition to aerobic exercise for 40 minutes, the patient underwent five to ten minute warm up and 10 minutes of stretching finals. During exercise, both groups used a heart rate monitor to control the intensity of exercise. CONDITION: C14.280.434 Chronic Heart Failure. Congestive heart failure. ; C14.280.434 ; I50.0 PRIMARY OUTCOME: After the intervention period of 12 weeks was found increased anti‐inflammatory marker (interleukin 10), together with a decrease in pro‐inflammatories markers(TNF alpha, inteleucina 6), it was observed increase tolerance to exercise over time during the exercise test with progressive loading, it was represented by an increase in peak oxygen consumption (VO2 peak). It was also found the increase relaxation of the cardiac muscle, which represents an improvement in diastolic function. The decrease in heart rate and blood pressure in resting and the increase in peripheral arterial blood flow was observed at the end of the study. There was a decrease on cell death associated with increased anti‐oxidant function. Finally it was found an improvement in quality of life. It is estimated that after 12 weeks of exercise training supervised will occur: it increase markers anti‐inflammatory (cytokines: interleukin 10 and 4). Decrease markers pro‐inflmatórios (cytokines: TNF alpha, one beta and inteleucina 6). It increase tolerance to exercise time during exercise testing with progressive loading, represented by peak oxygen consumption (peak VO2), it increase the volume of blood ejected by the left ventricle (ejection fraction in %), followed by further relaxation of the heart muscle (improvement of diastolic function). It decrease heart rate and resting blood pressure, an increase in peripheral blood flow arteries. It decrease cell death associated with increase anti‐oxidant function and improvement in quality of life. INCLUSION CRITERIA: Patients diagnosed with Chronic Heart Failure functional class II and III of Ischemic or hypertensive. Ejection fraction less than 45%. Male. Minimum age 35 years and and maximum of 80 years old. Clinically Stable and being Released by medical assistant to join the program of cardiopulmonary and metabolic rehabilitation through exercise. Not having made or had complications hospitalization in the last month. Sedentary.