To study the effect of Dextrose and PRP injections in Temporomandibular Joint Disorder Patients

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Group A‐ Platelet Rich Plasma : Group A‐ Autologous PRP was prepared from the patient s blood, which was collected during the same visit. The preparation was performed using a centrifugation machine operating at 220 V AC, 50 Hz, equipped with a built‐in speed regulator and a maximum speed of 3000 rpm. PRP was injected on Day 1 followed by follow up on day 15 and 1 Month Control Intervention1: Group B‐ Dextrose: Group B‐ 25 percent Dextrose injection, hypertonic solution containing 25 grams of dextrose per 100mL of water (0.25g/mL). Dextrose was injected on Day 1 followed by follow up on day 15 and 1 Month CONDITION: Health Condition 1: M249‐ Joint derangement, unspecified PRIMARY OUTCOME: VAS score, interincisal opening, joint sound, deviation or deflectionTimepoint: Baseline, 15 days and 1 Month SECONDARY OUTCOME: NILTimepoint: NIL INCLUSION CRITERIA: Clinically diagnosed cases of symptomatic internal derangement of temporomandibular joint. Patients no responded adequately to systemic medications and splint therapy. Patients provide informed consent and willing to participate in the study
Epistemonikos ID: 5acd0d31bbe5670559009e7b275f9e1a39eae4e4
First added on: Oct 08, 2026