Based on the effect of intestinal microecology on mitochondrial energy supply, this study explored the efficacy of Jiawei Qilang prescription in the treatment of drug-dependent constipation

INTERVENTION: treatment group:jiawei qilang power+Duphalacsimulation agent treatment;control group:jiawei qilang simulation power+Duphalac; CONDITION: Constipation PRIMARY OUTCOME: High‐throughput 16SrDNA sequencing and analysis of feces;5‐hydroxytryptamine; INCLUSION CRITERIA: The TCM diagnostic criteria of Qi‐Yin deficiency syndrome (refer to the consensus of TCM experts in diagnosis and treatment of constipation of spleen and stomach Disease Branch of Chinese Society of traditional Chinese Medicine (2017)) the main symptoms are as follows: reduced defecation frequency, prolonged defecation cycle, or difficult fecal quality, difficulty in defecation, or weakness in defecation. Secondary symptoms: Qi deficiency: 1) fatigue and lazy speech; 2) stupefaction; 3) abdominal distension and yin deficiency: 1) hand and foot heart heat; 2) body weight loss; 3) worry and lack of sleep. In line with at least 2 main symptoms, 2 secondary syndromes, qi deficiency and yin deficiency, each disease symptom grading and quantification combined with the guiding principles and related principles of clinical research of new drugs of traditional Chinese medicine. 2.2 Western diagnostic criteria: (1) constipation: the diagnostic criteria are established with re