Survey the effect of app-based acupressure therapy in patients with migraine pain in Mashhad population

INTERVENTION: Intervention 1: The intervention is acupressure, which is one of the therapeutic branches of Chinese medicine. Acupressure is pressure on specific points of the body, which are acupuncture points, by thumb pulp and with vertical pressure on the surface of the patient's body. The amount of pressure is such that the patient gets as close as possible to the bone below that point and feels pain. The treatment protocol consists of pressing each point for 3 minutes, and since we use 4 points, a total of 12 minutes in each patient's self‐treatment session. One treatment session per day and the duration of the treatment is 1 month. In this study, 4 mentioned acupuncture points are used for the intervention group. GV‐20, BL‐2, EX‐HN 5, LI‐4. Intervention 2: The same explanation given regarding intervention group 1 is also applicable in this group. But the points that are used in the control group are different and they are: LU‐7, GB‐21, ST‐36, TW‐17. CONDITION: G43.0 Migraine Headache. ; Migraine without aura PRIMARY OUTCOME: Pain severity. Timepoint: Before the intervention and 1 and 3 months after the intervention. Method of measurement: Using visual analogous scale (VAS). SECONDARY OUTCOME: Quality of life. Timepoint: Before the intervention and 1 and 3 months after the intervention. Method of measurement: WHO quality of life‐BREF 26 questionnaire. INCLUSION CRITERIA: Previous and definitive diagnosis of migraine (without aura) by a neurologist based on the criteria of the international association of Headache ( IHS) at least 6 months ago (upload the latest prescription for migraine treatment by a neurologist) Experiencing acute migraine at a frequency of 2‐8 times per month for the previous 3 months Being in the age range of 18‐45 years Absence of pregnancy and breastfeeding Absence of other neurological diseases Absence of cancer and skin malignancy or wound in the acupressure area All eligible participants must be able to understand the research instructions and be willing to give informed consent. All participants should answer and complete the entire designed questionnaires All participants should provide a daily report of the severity, duration, and number of migraine attacks