Effects of Images Following Long-term Aerobic Exercise on Brain Activation

Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2014
The primary purpose of this study is to quantify activation of regions of the brain associated with appetite and reward after viewing high sugar and high fat (HS/HF) images compared to control images following long-term aerobic exercise. 1. After long-term aerobic exercise compared to a no-exercise control group, viewing HS/HF food images vs. control images will result in higher activation of regions of the brain associate with appetite (hypothalamus). 2. After long-term aerobic exercise compared to a no-exercise control group consumption of a sucrose solution compared to an artificially sweetened solution and a tasteless solution, viewing HS/HF food images vs. control images will result in lower activation of regions of the brain associated with reward \[amygdala, anterior cingulate cortex (ACC), Orbitalfrontal Cortex (OFC), and ventral tegmental area (VTA), striatum, insula\] in overweight and obese men and women. Exploratory Aims As exploratory aims, investigators will test a preliminary brain connectivity analysis.
Epistemonikos ID: 58f9b07f86322ab4afe3ac026a87a44b44d50467
First added on: May 11, 2024