Flucloxacillin Results in Suboptimal Plasma Voriconazole Concentrations.

Category Primary study
JournalAntimicrobial agents and chemotherapy
Year 2017
Combining voriconazole and flucloxacillin is indicated in patient cohorts experiencing both invasive aspergillosis and Gram-positive infections (e.g., patients with chronic granulomatous disease or postinfluenza pulmonary aspergillosis). We report a highly relevant interaction between voriconazole and flucloxacillin, resulting in subtherapeutic plasma voriconazole concentrations in more than 50% of patients, that poses a severe threat if not managed properly.
Epistemonikos ID: 58b1ec000d6ba84493da46997fc3968689d352b9
First added on: Nov 02, 2024