Effect of Food on the Pharmacokinetics of Decitabine/Tetrahydrouridine Combination Capsules in Healthy Adult Subjects

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2019
This study is to evaluate the relative pharmacokinetics of oral decitabine and tetrahydrouridine (THU) after a high‐fat, high‐calorie (FDA standard) meal as compared to decitabine and THU under fasting conditions in healthy adult male and female subjects. In addition, this study is to compare the pharmacokinetic parameters between male and female subjects, and also to capture safety information for the decitabine and THU combination in healthy subjects after oral dosing.
Epistemonikos ID: 5800b2ee13a2df7f900190632a57c9c7d496bf0c
First added on: May 22, 2024