Impact of Glycopyrrolate on Carotid Angioplasty and Stenting

INTERVENTION: Glycopyrrolate 1. Dosage of drug: Glycopyrrolate 0.2‐0.4mg Frequency: Once only at not less than 6 mins before balloon inflation but not more than 2 hours before balloon inflation Mode: intravenous 2. Intervention group: Receives glycopyrrolate 3. Control group: Receives normal saline (placebo) 4. Duration of intervention: Once only administration of glycopyrrolate given as detailed above. CONDITION: Carotid angioplasty and stenting for carotid stenosis PRIMARY OUTCOME: Reduction in intra‐operative bradycardia and/or hypotension SECONDARY OUTCOME: Reduction in post‐operative cardiovascular and neurological morbidity and mortality. INCLUSION CRITERIA: All patients for carotid angioplasty and stenting.