Cognitive-behavioural therapy and motivational intervention for schizophrenia and substance misuse - 18-month outcomes of a randomised controlled trial

This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Compared with routine treatment, the integrated programme of cognitive-behavioural therapy (CBT) combined with motivational intervention (MI) for patients with psychosis and substance use resulted in significant improvements in patient functioning. In addition, the benefits persisted for up to 18 months. The experimental intervention was no more costly than routine care (RC), and there was a high probability of it being cost-effective.