Poly-L-Lactic Acid Threads Versus Platelet-Rich Plasma for Post-Traumatic Atrophic Scars

Post‐traumatic atrophic scars result from abnormal healing following skin injury and maycause significant cosmetic and functional impairment. Subcision releases the fibrousbands tethering the scar to deeper tissues and may improve the response to additionaltreatments. PLLA threads are biodegradable materials that can stimulate collagenproduction, while PRP contains concentrated platelets and growth factors that may enhancetissue repair and remodeling.This comparative study was conducted at the Dermatology and Venereology Department, TantaUniversity Hospital. Patients diagnosed with post‐traumatic atrophic scars for at leastone year and who had not received treatment during the preceding six months wereenrolled. Patients with keloids, immunosuppression, coagulative or thrombophilicdisorders, or chronic diseases were excluded.Participants were divided into two equal treatment groups. Group A received a singlesession of subcision followed by insertion of poly‐L‐lactic acid threads. Group Breceived subcision combined with PRP injection for four sessions at one‐month intervals.Clinical photographs were obtained before treatment and three months after treatment.Clinical improvement was assessed by two blinded dermatologists using the GlobalAesthetic Improvement Scale, while patient satisfaction and treatment‐related complaintsor adverse effects were also recorded.Skin biopsies were obtained from six patients before treatment and three months aftertreatment and evaluated using hematoxylin and eosin and trichrome staining to assesshistopathological changes. All patients were followed for three months.The study was approved by the Research Ethics Committee of the Faculty of Medicine, TantaUniversity, with approval number 32889/01/19, and informed consent was obtained from allparticipants.