Clinical evaluation of efficacy and safety of La Roche-Posay New B5 Multi-Repair Cream combined with intense pulsed light for improving rosacea

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: Test side (half face):La Roche‐Posay New B5 Multi‐Repair Cream, applied twice daily (morning and evening) to one half of the face;Control side (half face):Regular moisturizer (control cream), applied twice daily (morning and evening) to the other half of the face; CONDITION: Rosacea PRIMARY OUTCOME: Clinician's Erythema Assessment (CEA);Investigator Global Assessment (IGA); SECONDARY OUTCOME: stratum corneum hydration;transepidermal water loss (TEWL);Quantitative Erythema Measurement;sebum level;VISIA imaging analysis;Subjective Skin Sensitivity Self‐evaluation;Investigator Treatment Satisfaction Evaluation;Subject Treatment Satisfaction Self‐evaluation;Subject self‐assessment of treatment compliance; INCLUSION CRITERIA: 1. Chinese males and females aged 18‐45 years (inclusive), in generally good condition. 2. Diagnosed with facial rosacea (according to the *Chinese Guidelines for the Diagnosis and Treatment of Rosacea 2021 Edition*), erythematotelangiectatic type, with persistent erythema as the main manifestation, in the stable phase of skin lesions, accompanied by skin sensitivity symptoms, and meeting the indications for IPL treatment. 3. Signed informed consent personally. 4. Good oral and written communication and comprehension skills. 5. Good compliance with the study protocol, willingness to use the products provided by the study according to the protocol throughout the study period, not to use other drugs or products, to complete diaries, and to attend scheduled follow‐up visits.
Epistemonikos ID: 54b30a5bfaec3f7544e2a3a3f93c2ab1640b14fa
First added on: Oct 08, 2026