A Case of Repeated Measurement of Antibody for Covid-19 Evoked Having Common Variable Immunodeficiency (Cvid)

A 43-year-old female who was diagnosed with coronavirus disease 2019 (COVID-19) seventeen days before was transferred to our hospital because of fever and cough. Computed tomography (CT) showed consolidations in both lung fields, and we diagnosed COVID-19 pneumonia. After the addition of remdesivir and baricitinib, her symptoms improved. However, on day 19 a fever was observed, and CT also showed new consolidations. Genomic analysis revealed a different type from the first infection. Furthermore, repeated measurement of antibodies against SARS-CoV-2 revealed no antibody production. She was diagnosed with immunodeficiency and recovered completely with the use of immunoglobulins and antibody preparations for COVID-19.