Investigation of the Application and Mechanism of Anti-Itch Wash in Perianal Eczema Based on the NF-?Bp65 Pathway

Authors
Category Primary study
Registry of TrialsInternational Traditional Medicine Clinical Trial Registry
Year 2026
INTERVENTION: High concentration of traditional Chinese medicine group (20%):Mi Xthe anti‐itch lotion with warm water in a 1:4 ratio to make a diluted solution.;Medium concentration group of traditional Chinese medicine (10%):Mi Xthe anti‐itch lotion with warm water in a 1:9 ratio to make a diluted solution.;Low concentration of traditional Chinese medicine group (5%):Mi Xthe anti‐itch lotion with warm water in a 1:19 ratio to make a diluted solution.;Control group:Compound Huangbai liquid; CONDITION: Perianal eczema PRIMARY OUTCOME: Perianal itch points;Rash morphology integral;Integral area of skin lesions; SECONDARY OUTCOME: TNFa IL6; INCLUSION CRITERIA: 1) Aged between 18 and 65 years, male or female; 2) Meeting the diagnostic criteria for perianal eczema; 3) Meeting the traditional Chinese medicine diagnostic criteria for perianal eczema of the Damp‐Heat in Lower Energizer pattern; 4) No use of relevant medications (including Chinese and Western medicines) within the past two weeks; 5) Agreement to participate in this trial and voluntarily signing the informed consent form.
Epistemonikos ID: 539e812d1efdca68fe0d15cad8a9efdf41afc41d
First added on: Aug 10, 2026