Efficacy and Safety of Magnetic Seizure Therapy versus Modified Electroconvulsive Therapy for Refractory Obsessive-Compulsive Disorder: a Multicenter, Double-Blind, Parallel-Group, Randomized Controlled Trial

INTERVENTION: MECT group:Modified Electroconvulsive Therapy;MST group:Magnetic Seizure Therapy; CONDITION: refractory obsessive‐compulsive disorder PRIMARY OUTCOME: Changes in Y‐BOCS scores from baseline to after the 12th treatment; SECONDARY OUTCOME: Changes in neurocognitive function scores; INCLUSION CRITERIA: 1.Age between 16 and 65 years (inclusive); 2.Meet the preliminary diagnostic criteria for obsessive‐compulsive disorder in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM‐5); 3.Meet the definition of treatment‐refractory illness, defined as no response to adequate and sufficient courses (>8 weeks) of at least two anti‐obsessive‐compulsive medications with different mechanisms of action; 4.Y‐BOCS total score = 16; 5.The subject and his/her family have been informed of the study and voluntarily provided written informed consent.