Effectiveness Fluoride Varnishes in Children With Early Childhood Caries

Duraphat (Colgate), which we used as a positive control group in our study, contains only 5% sodium fluoride. It has been reported in studies that Duraphat is effective in remineralization. Clinpro ™ White Varnish, another topical varnish in this study,was reported to be effective for caries prevention in pre‐school children. One of the varnishes we evaluate in the study, Embrace™ Varnish, contains 5% sodium fluoride with xylitol‐coated calcium and phosphate. According to the manufacturer, the xylitol coating prevents the calcium and phosphate salts from reacting until they come in contact with saliva. Saliva dissolves the xylitol and releases the calcium and phosphate ions, which react with the fluoride ions in saliva to form protective fluorapatite on the teeth19 MI Varnish, in the fourth group containing 5% sodium fluoride with casein phosphopeptide amorphous calcium phosphate (CPP‐ACP) had a high release of calcium and fluoride ions.