Diabetes Remission After RYGBP and RYGBP With Fundus Resection

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2023
The goal of this randomized clinical trial is to evaluate glycemic control in patients with morbid obesity and type 2 diabetes after Roux-en-Y gastric bypass (RYGBP) and RYGBP with fundus resection. The main questions to answer are: * Rate of diabetes remission and the role of the gastrointestinal hormones * Whether fundus resection leads to improved glycemic control Patients will randomly undergo typical RYGBP or RYGBP with fundus resection. Gastrointestinal hormones profile \[ghrelin, glucagon-like peptide-1 (GLP-1), peptide YY (PYY), glucagon\], glucose levels and insulin response will be measured preoperatively, at 6 months and at 12 months, during 120-min OGTT.
Epistemonikos ID: 527f78d810550dfae091c5fee902892d644ee8f7
First added on: Feb 19, 2024