Multiple myeloma lifestyle study

INTERVENTION: Patients are randomised to either a control group or to receive a physical activity intervention. Patients in the control group receive usual care which includes their regular check‐ups in the UCLH myeloma clinic and/or their local hospitals and receiving maintenance or consolidation treatment, if applicable. Patients in the treatment arm are offered a physical activity programme, led by a physiotherapist, which requires them to attend a hospital gym once a week as well as carry out a home‐based programme of exercises two days a week. After the 3 months patients attend the gym once a month and follow a home‐based exercise programme three days a week for 3 additional months. Patients in both control and intervention groups are assessed in terms of outcome measures at 3, 6 and 12 months follow up. Follow Up Length: 12 month(s) CONDITION: Topic: Cancer; Subtopic: Haematological Oncology; Disease: Myeloma ; Cancer PRIMARY OUTCOME: Fatigue; Timepoint(s): baseline, 3, 6 and 12 months SECONDARY OUTCOME: 1. Anxiety and depression; Timepoint(s): baseline, 3, 6 and 12 months; 2. Body mass and body composition; Timepoint(s): baseline, 3, 6 and 12 months; 3. Diet; Timepoint(s): baseline, 3, 6 and 12 months; 4. Exercise capacity and cardiorespiratory fitness; Timepoint(s): baseline, 3, 6 and 12 months; 5. Haematology, biochemistry, bone health markers (basic ALP, osteocalcin); Timepoint(s): baseline, 3, 6 and 12 months; 6. Muscle strength and endurance; Timepoint(s): baseline, 3, 6, 12 months; 7. Physical activity; Timepoint(s): baseline, 3, 6 and 12 months; 8. Resting blood pressure; Timepoint(s): baseline, 3, 6 and 12 months; 9. Self‐efficacy; Timepoint(s): baseline, 3, 6 and 12 months; 10. Sleep quality; Timepoint(s): baseline, 3, 6 and 12 months; 11. Well‐being; Timepoint(s): baseline, 3, 6 and 12 months INCLUSION CRITERIA: 1. Myeloma survivors, who are assigned to UCLH myeloma clinics 2. Stable disease for at least 6 weeks, off treatment or on maintenance or consolidation treatment 3. Ability to give informed consent 4. A good performance status (ECOG 02) 5. Clinically able to carry out an exercise training programme on a regular basis (assessed by initial screening) 6. Aged at least 18