Clinical Trial of corneal crosslinking for keratoconus and keratoectasia

INTERVENTION: corneal crosslinking with removal of corneal epithelium corneal crosslinking without removal of corneal epithlium CONDITION: Keratoconus, Keratoectasia PRIMARY OUTCOME: Uncorrected and best corrected visual acuity, maximum corneal refractive power in corneal topography SECONDARY OUTCOME: corneal thickness measured by anterior segment OCT INCLUSION CRITERIA: 1) Those whose age at obtaining informed consent meet following criteria Keratoconus: 14 years old and more Keratoectasia: 20 years old and more 2) Those whose diagnosis by corneal topography is keratoconus, keratoconus suspect or keratoectasia 3) The thinnest corneal thickness is over 400 micron meter. In the case that corneal thickness is less than 400 micron meter, it is necessary of more than 400 micro meter of corneal thickness during surgery after adding hypotonic riboflavin solution. In case without removal of corneal epithelium, the criteria is more than 380 micro meter of corneal thickness. 4) Progressive keratoconus or keratoectasia meeting any of the following criteria; ‐the maximum corneal refractive power (Kmax) increases of more than 1 diopter ‐manifest astigmatism increases of more than 1 diopter ‐manifest spherical equivalent increases more than 1 diopter ‐base curve of hard contact lenses decreases of more than 0.1mm

Epistemonikos ID: 51994a116077731d15edcb38e2a98a54710337b9
First added on: Aug 22, 2024