Cost-effectiveness of sibutramine in the LOSE Weight Study: evaluating the role of pharmacologic weight-loss therapy within a weight management program

This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Sibutramine plus a weight management programme (WMP) led to a significant greater reduction in weight than the WMP alone. However, such weight loss was achieved at higher cost than that associated with patients receiving the WMP alone.