Pre-diabetes system evaluation of acupuncture intervention

Objective: Systematic evaluation of the effectiveness and safety of acupuncture intervention in pre-diabetes. Method: By retrieving the China Knowledge Database (CNKI), VIP Chinese Database (VIP), Wanfang Chinese Journal Database, Chinese Biomedical Literature Database (CBM), PubMed, EmBase, ClinicalTrails.gov, Cochrane Fig. Library Self-Build Library A randomized controlled trial of pre-diabetes acupuncture intervention by 8 November 2016, screening studies that met the criteria for incorporation. Methodological quality evaluation using the Cochrane randomized controlled trial bias risk assessment table, statistical analysis using the RevMan 5.3 software. Results: 11 studies, including 970 participants Subject. Methodological quality of inclusion in research Low, 6 studies were randomized grouping using stochastic numerical tabulation, and one study described the hidden and blind method of stochastic scheme allocation. The inverted funnel diagrams of fasting blood sugar in patients after acupuncture treatment were analyzed. Effect of acupuncture on normal sugar tolerance conversion in prediabetic patients, two of which show that acupuncture can promote Syners' sugar tolerance normalization, 1 showing the difference between acupuncture combined lifestyle intervention and lifestyle intervention alone in promoting the normalization of sugar tolerance in patients (P>0.05). This study cannot assess acupuncture due to the limited number of studies and differences in clinical study observation indicators. Effects on improving blood glucose, glycosylated hemoglobin, body mass index, insulin resistance .Only 1 out of 11 randomized controlled trials observed adverse reactions and clearly indicated the absence of adverse reaction events. Sensibility Analysis and Meta Analysis Conclusions: Acupuncture may have some efficacy in prediabetes , but due to the small sample size and low methodological quality included in the study, the available evidence is insufficient to demonstrate the effectiveness and safety of acupuncture intervention in pre-diabetes, and its potential efficacy needs to be confirmed by high-quality randomized controlled trials.