Authors
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Saglik Bilimleri Universitesi -More
Category
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Primary study
Registry of Trials»ClinicalTrials.gov
Year
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2026
This study was planned to determine the effect of integrative therapies on fatiguemanagement and quality of life in cancer patients undergoing immunotherapy. It wasdesigned as a randomised controlled experimental type study determined by simple randomsampling method.Hypotheses of the Study H1: There is a significant difference in terms of fatigue levelbetween the intervention group and the control group in which music recital and yogapractice were performed in cancer patients receiving immunotherapy.H2: There is a significant difference between the intervention group and the controlgroup in terms of quality of life level in cancer patients receiving immunotherapy.Variables of the Study Independent Variables: Age, occupation, marital status, educationlevel, chronic diseases, medications, smoking, alcohol consumption status.Dependent Variables: Fatigue, quality of life. Controlled Variables: Yoga practices,music recitalPlace and Time of the Research The study was conducted in the medical oncology outpatientclinic of the internal medicine department of a state university hospital in Istanbul.Inclusion Criteria ‐ Receiving immunotherapy treatment for cancer diagnosis, ‐ Reads and writes, ‐ Over 18 years old, ‐ Able to communicate, no language problems, ‐ Those who volunteered to participate in the study and whose consent was obtained, ‐ Not diagnosed with a mental or psychiatric illness, ‐ Patients without hearing impairment were included in the study. Exclusion Criteria ‐ Unable to adapt to planned interventions, ‐ Hearing impaired, ‐ Not volunteering to participate in the study, ‐ Patients with mental disability or perception problems were not included in thestudy.ENSURING RANDOMISATION IN THE STUDY Before the data collection phase, simple randomsampling method was used to ensure that the participants to be included in the study hadequal rights.With the computer‐based randomisation method, the participants were numbered according tothe order of arrival and divided into group 1 intervention group and group 2 controlgroup.Collection of Pranayama Group Data Patient Information Form, FACT‐G Quality of Life Scaleand Hirai Cancer Fatigue Scale were filled in the first interview. Pranayama breathingexercise was performed by the practitioner for 20 minutes before the immunotherapyapplication. For the application, a quiet room with limited entrance and exit, which wasreserved for injection applications within the unit, was preferred. After theapplication, the patient was taken to the treatment department for immunotherapytreatment and was allowed to listen to music with headphones during immunotherapytreatment. The patient was contacted by phone to listen to music and do pranayamaexercise at least 3 days a week for 8 weeks following the treatment. The application wasrepeated before each immunotherapy and the application was continued for a total of 8weeks. The FACT‐G Quality of Life Scale and Hirai Cancer Fatigue Scale ed by face‐to‐faceinterviews with the patient in the fourth and eighth weeks.Collection of Control Group Data Patient Information Form, FACT‐G Quality of Life Scaleand Hirai Cancer Fatigue Scale were filled in the first interview. Patients in thecontrol group were not treated before immunotherapy, standard immunotherapy treatment wasapplied. The FACT‐G Quality of Life Scale and Hirai Cancer Fatigue Scale were filled inthe fourth and eighth week following the treatment and the patients were followed up foreight weeks
Epistemonikos ID: 512d06015533413367840d57a2821b3fb99dea91
First added on: Aug 11, 2026