A Single-Center, Randomized, Double-Blind, Controlled Clinical Study on Nano Selenium Capsules Combined with CO2 Laser Therapy for Condyloma Acuminatum

INTERVENTION: Placebo group :Placebo capsules + CO2 laser therapy;Experimental group:SeNPs Capsules + CO2 laser therapy; CONDITION: Condyloma acuminatum PRIMARY OUTCOME: Recurrence‐Free Survival; SECONDARY OUTCOME: Change in the weekly percentage of days with symptoms at Weeks 4, 8, 12, and 16;Percentage of subjects with UAS7 <= 6 at week 12;Change from baseline in HSS7 at weeks 4, 8, 12, and 16;Change in weekly rescue medication use at weeks 4, 8, 12, and 16.;Change in percentage of subjects with HSS7 <= 3 at weeks 4, 8, 12, and 16;Change in the percentage of subjects with UAS7 = 0 at weeks 4, 8, 12, and 16;Change in the weekly peak itch VAS score at weeks 4, 8, 12, and 16;Time to first use of rescue medication;Change in the percentage of subjects with HSS7 = 0 at weeks 4, 8, 12, and 16;Change in percentage of subjects with lSs7 =0 at weeks 4, 8, 12, and 16;Change in percentage of subjects with lSS7 <= 3 at weeks 4, 8, 12, and 16;Change from baseline in ISS7 at weeks 4, 8, 12, and 16;Proportion of subjects with a UAS7 reduction from baseline of >=11 points at Weeks 4, 8, 12, and 16; INCLUSION CRITERIA: 1. Age between 18 and 75 years old (inclusive), any gender; 2. Diagnosed with genital warts through clinical examination (visual inspection) and 5% acetic acid test; 3. Treatment history: first‐time occurrence, or if recurrent, at least 4 weeks have passed since the last treatment (such as medication, cryotherapy, electrocautery, CO2 laser, photodynamic therapy, etc.) and the original lesions have completely healed; 4. Informed consent: willing to participate in this study, able to understand the study procedures, and sign a written informed consent form; 5. Compliance: committed and willing to complete all visits, treatments, and follow‐ups according to the protocol, and follow all study rules (such as sexual activity restrictions); 6. Agree to participate in follow‐up and sign the informed consent form.