The effect of consuming the liposomal form of pistachio kernel oil on multiple sclerosis

INTERVENTION: Intervention 1: Intervention group: once a day, 5 ml, liposomal form of 10% pistachio kernel oil, orally, for 24 weeks. In this study, no special equipment is used and the explanations of this trial are given in printed form to the volunteers. Of course, entering this study does not require special training. The liposomal form of pistachio kernel oil is also prepared and approved by the Research Institute of Basic Medical Sciences of Rafsanjan University of Medical Sciences. Intervention 2: Control group: This group will be given the same as the placebo test group with the same intervention group program. In this study, no special equipment is used and the explanations of this trial are given in printed form to the volunteers. Of course, entering this study does not require special training. Pharmacopoeia is also prepared and approved by the Research Institute of Basic Medical Sciences of Rafsanjan University of Medical Sciences. CONDITION: Multiple Sclerosis (MS). ; Multiple sclerosis PRIMARY OUTCOME: Concentration of inflammatory and anti‐inflammatory factors. Timepoint: Intervention time (w0), 6 weeks after intervention (w6), 12 weeks after intervention (w12), 18 weeks after intervention (w18) and 24 weeks after intervention (w24). Method of measurement: With ELISA Kit. Relative expression of genes of receptors of inflammatory and anti‐inflammatory agents. Timepoint: Intervention time (w0), 24 weeks after intervention (w24). Method of measurement: By Realtime PCR. The length and severity of the disease. Timepoint: Intervention time (w0), 6 weeks after intervention (w6), 12 weeks after intervention (w12), 18 weeks after intervention (w18) and 24 weeks after intervention (w24). Method of measurement: According to the descriptive measurement of disability rate. SECONDARY OUTCOME: Allergies to pistachio compounds. Timepoint: Intervention time (w0), 6 weeks after intervention (w6), 12 weeks after intervention (w12), 18 weeks after intervention (w18) and 24 weeks after intervention (w24). Method of measurement: Qualitative examination with patient self‐declaration. INCLUSION CRITERIA: Women aged 18 to 51 years Definite diagnosis of multiple sclerosis with a descriptive measure of disability rate between 1 to 3