The effect of ginger on glycemic status, apolipoprotein B, apolipoprotein A-I, total antioxidant capacity (TAC), malondialdehyde (MDA), high sensitivity c-reactive protein (hsCRP), and paraoxonase in type 2 diabetic patiants

INTERVENTION: control group : lactose supplement, 2 grams per day and during 3 months Intervention 1: intervention group : ginger supplement, 3 gram per day and during 3 months. Intervention 2: control group : lactose supplement, 2 grams per day and during 3 months. intervention group : ginger supplement, 3 gram per day and during 3 months Treatment ‐ Drugs CONDITION: type 2 diabetese melitus. ; R81 PRIMARY OUTCOME: Apo A. Timepoint: before & after intervention (3 months later). Method of measurement: immunotorbidometry. Apo B. Timepoint: before & after intervention (3 months later). Method of measurement: immunotorbidometry. Apo B/Apo A‐I. Timepoint: before & after intervention (3 months later). Method of measurement: ratio. Fasting blood sugar. Timepoint: before & after intervention (3 months later). Method of measurement: glucose oxidase method. Hb A1C. Timepoint: before & after intervention (3 months later). Method of measurement: colorimetry. High‐sensitivity C‐Reactive Protein. Timepoint: before & after intervention (3 months later). Method of measurement: ELISA kitt. Insulin resistance. Timepoint: before & after intervention (3 months later). Method of measurement: insulin × glucose / 22.5. Insulin. Timepoint: before & after intervention (3 months later). Method of measurement: IRMA. Malondealdehyde. Timepoint: before & after intervention (3 months later). Method of measurement: colorimetry. Paraoxonase. Timepoint: before & after intervention (3 months later). Method of measurement: colorimetry. Total antioxidant capacity. Timepoint: before & after intervention (3 months later). Method of measurement: colorimetry (FRAP). INCLUSION CRITERIA: INCLUSION CRITERIA:Non‐insulin dependent diabetic patients with type 2 diabetes that is diagnosed by a physician, Endocrinologist.Diabetes duration of at least 2 years , 20‐60 ages,Hb A1c :6‐8% , Lack of antioxidant supplements such as selenium, zinc, beta carotene, and ... At least 3 months before the study ‐ not smoking, and alcohol ‐ a willingness to cooperate with exclusion criteria: Patient unwillingness to continue with the plan ‐ changes in type or dose of medication, Changes in diet or physical activity every day ‐ taking any antioxidant supplements ‐ taking less than 80% of supplements given to patients at baseline(the compaliance lower than %80),Recent receive insulin ‐ pregnancy and lactation ‐ renal , hepatic , thyroid diseases and anemia ‐ hypersensitivity to the drug