Online Mindfulness-Based Cognitive Therapy for People With Multiple Sclerosis With Mild-Moderate Depression

This study will use a waiting list randomized controlled trial design with amixed‐methods research approach, including both quantitative and qualitative methods.Randomization helps minimize research bias and controls for participant and contextualfactors that might otherwise make interpretation of results challenging. We will recruit152 people with multiple sclerosis (PwMS) with any type of MS, who also havemild‐moderate depression, aged 18 or greater, and able to understand spoken and writtenEnglish.For the quantitative part, we will examine how much change in depression there isfollowing mindfulness‐based cognitive therapy (MBCT), as well as whether participantsattend the course and complete study measures or not, and how much participants completeMBCT home practices. We will also examine how much change there is in fatigue, sleeppain, quality of life, and anxiety.For the qualitative part of the study, we will use semi‐structured interviews to exploreparticipant experiences of online MBCT, how people used online MBCT, what worked, whatdidn't and why, how online MBCT impacted self‐management of depression, and suggestionsfor improving the course to make it more relevant for PwMS with depression.