Outcomes of Macular Hole Surgery With Inverted Flap With vs Without Post op Posturing With SF6 in Macular Hole More Than 400 Micrometres

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This study evaluated the outcomes of surgery for large full‐thickness macular holesmeasuring more than 400 micrometres using the inverted internal limiting membrane flaptechnique with sulphur hexafluoride (SF6) gas tamponade. The study was conducted at theDepartment of Ophthalmology, Lahore General Hospital, Lahore. A total of 52 male andfemale patients aged 52‐84 years with full‐thickness macular holes were included.All patients underwent 23‐gauge pars plana vitrectomy with hyaloidectomy and invertedinternal limiting membrane flap surgery after staining with 0.05% Brilliant Blue.Patients were divided into two groups according to postoperative positioning. One groupperformed postoperative face‐down posturing, whereas the other group did not performface‐down posturing. The study examined whether successful closure of large macular holescould be achieved without postoperative face‐down positioning after surgery with SF6 gastamponade.Patients were followed on postoperative days 1, 7, 30, and 90. The main outcome wasanatomical closure of the macular hole, which was assessed using optical coherencetomography (OCT). Successful treatment was defined as complete anatomical closure of themacular hole. The outcomes of patients who performed face‐down posturing were comparedwith those who did not perform postoperative posturing to determine whether face‐downpositioning was necessary following surgery for macular holes larger than 400micrometres.
Epistemonikos ID: 4f7f107fefa2c482cbb1535cdbfda9e929f18bc6
First added on: Aug 26, 2026