comparison of two different combination of anaesthesia drugs for laparoscopic hysterectomy surgeries to decrease the dose of opioids.

INTERVENTION: Intervention1: Opioid Sparing Anaesthesia: patients in Opioid sparing Anaesthesia group will receive Inj.Dexmedetomidine 0.5mcg/kg i.v, Inj.Paracetamol 1gm i.v,Inj.Dexamethasone 8mg , Inj.Ketamine 0.5 mg/kg before induction of Anaesthesia. After induction of anaesthesia these patients will receive inj.Dexmedetomidine infusion at the rate of 0.5mcg/kg/hour, sevoflurane 1‐2% for maintenance of anaesthesia. Control Intervention1: Opioid Based Anaesthesia: patients in opioid based anaesthesia group will receive Inj.Fentanyl 2mcg/kg i.v before induction of Anaesthesia . After induction of anaesthesia these patients will receive Inj.Fentanyl 0.5mcg/kg/hour as infusion, sevoflurane 1‐2% for maintenance of Anaesthesia. CONDITION: Health Condition 1: O‐ Medical and Surgical Health Condition 2: O‐ Medical and Surgical PRIMARY OUTCOME: Blood pressure and heart rate to pneumoperitoneumTimepoint: baseline, 1 minute, 3minutes,5 minutes,10 minutes and 15 minutes SECONDARY OUTCOME: hypotension at induction ; response to extubation ; fentanyl requirement ; time for extubation ; sedation & analgesia in recovery roomTimepoint: baseline , during surgery & upto 120 minutes after surgery INCLUSION CRITERIA: 1.American Society of Anaesthesiologists I,II 2.Age 18‐65 years 3.BMI 18‐30 kg/m2 4.patients undergoing laparoscopic gynaecological surgeries