Clinical Observation of Modified Xiaobanxia Fuling Decoction on Cancer Chemotherapy Vomiting

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Authors
Category Primary study
Journal中国中医急症(Chinese TCM Emergencies)
Year 2020
OBJECTIVE: To observe the clinical efficacy of modified Pinellia Pinellia Fuling Decoction in the treatment of cancer chemotherapy vomiting. METHODS: 120 cases of cancer patients were randomly divided into a control group and a treatment group of 60 cases each. The control group was treated with conventional Western medicine; the treatment group was treated with Pinellia Pinellia Fuling decoction on the basis of the control group. Rectal instillation treatment of decoction. Compare the clinical efficacy and vomiting recurrence rate of the two groups of patients. RESULTS: After treatment, the total clinical effective rate of the treatment group was 83.33%, which was higher than the 58.33% of the control group (P<0.05); the treatment group was treated for 24 , 48, 72, and 96 hours, the number of vomiting was lower than that in the control group (P<0.05). After treatment, the quality of life scores of the treatment group and control group were (83.61±5.82) points and (71.36±6.21) points respectively, which were higher than Compared with (63.51±5.05) points and (64.34±5.12) points before treatment (P<0.05); compared with the control group, the improvement in the treatment group was more obvious (P<0.05). The improvement of immune function of patients in the treatment group was significantly better than Control group (P<0.05). The two groups were followed up for 1 week after treatment. There were 4 cases of recurrence of vomiting in the treatment group, with a recurrence rate of 6.67%; 10 cases of recurrence in the control group, with a recurrence rate of 16.67%. Comparing the recurrence rates of the two groups, the difference was statistically significant. (P<0.05). Comparison of the curative effects of TCM syndromes between the two groups after treatment. The therapeutic group’s TCM syndrome curative effects were generally better than those of the control group (P<0.05). During the medication period, patients in the treatment group and the control group did not have rashes, drug eruptions, etc. Allergic reactions, constipation, abdominal distension, dizziness and other adverse reactions in the treatment group after treatment were less than those in the control group (P<0.05), and there were no abnormalities in heart, liver and kidney function in both groups. CONCLUSION: Integrated traditional Chinese and Western medicine is more clinically effective in treating cancer chemotherapy vomiting and recurrence Rate is low
Epistemonikos ID: 4de03b0973afb68494c6cb1de0a828ac419b6255
First added on: Dec 06, 2023
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