Effect of Empagliflozin in Patients With eGFR Between 10 and 20 ml/Min/1.73m2

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
The proximal tubule remains the main site for sodium reabsorption in patients with advanced renal failure. The investigators therefore hypothesize that SGLT2i should still exert a significant natriuretic effect in patients with eGFR below 20 ml/min/1.73m2, and therefore should still decrease proteinuria with a potential renal protective effect.
Epistemonikos ID: 4cd064659543d22eb017ba7f4e8cfed75250094e
First added on: Jul 22, 2025