针刺治疗绝经过渡期绝经相关症状的临床研究

目的:客观评价针刺对绝经过渡期(MT)绝经相关症状的疗效以及针感得气对疗效的影响. 方法:将90例患者随机分配到针刺组(30例)、安慰针组(30例)和穴位浅刺组(30例).采用平均24h烘热积分、绝经症状评价量表(MRS)作为主要评价指标进行评价. 结果:①3组患者的平均24h烘热积分、MRS量表得分经多元方差分析,组间差异均有统计学意义(P＜0.05).②3组患者平均24h烘热积分各时点两两比较的结果显示,针刺组与穴位浅刺组比较,差异无统计学意义;针刺组、穴位浅刺组分别与安慰针组比较,差异均有统计学意义(P＜0.05).③3组患者MRS量表各时点两两比较,治疗第4周,针刺组与安慰针组比较,差异有统计学意义(P＜0.05),穴位浅刺组分别与针刺组、安慰针组比较,差异均无统计学意义;其余各时点两两比较均有统计学差异(P＜0.05),其中针刺组降分幅度最大,浅刺组次之,安慰针组最小. 结论:针刺治疗MT绝经相关症状是一种有效安全的方法;针刺得气与否可影响针刺的疗效.; Objective: To assess curative effect of acupuncture and Deqi on the treatment of menopause-related symptoms of menopause transition.Methods: Ninty patients were randomly divided into three groups: acupuncture group (30patients), sham acupuncture group (30 patients) and shallow acupuncture group (30 patients).24h hot flush scores and menopause rating scale questionnaires(MRS) were used to measure the outcomes.Results: ①Variance analysis of hot flush scores and MRS scores showed significant differences between the groups (P<0.05).②For hot flush scores, multiple comparisons did not show differences between acupuncture group and shallow acupuncture group; Both acupuncture group and shallow acupuncture group had significant differences to sham acupuncture group.③③For MRS scores, differences in every two groups were significant(P<0.05), acupuncture group decreased the most, followed with the shallow group and sham group.Conclusion: Analysis results of the trial indicated that acupuncture is safe and has effective on menopause-related symptoms of menopause transition, and Deqi could affect the efficacy of acupuncture in the treatment of menopause transition