Comparative Study of The Efficacy and Safety of Subcision Combined With Injection of Exosomes Versus Subcision Alone in Treatment of Atrophic Post- Acne Scars.

This split-face comparative prospective study was carried out on 20 patients presenting with atrophic post-acne scars. All participants were subjected to full history taking, general and dermatological examination, photographing before, during and after the end of the treatment. On the right side, combined subcision with exosomes injection was performed, whereas subcision alone was performed on the left side. Three treatment sessions were administered at 4-week intervals, followed by monthly follow-up for 3 months. Before the treatment sessions, patients were instructed to put topical anesthetic cream. During sessions, the treated areas were disinfected by alcohol 70%,1 ml of lidocaine Hcl 2% was administered into the treatment site at the subdermal level, subcision was done on both sides followed by 1 ml of intralesional exosome injection on the right side only. After sessions, patients were advised to put topical antibiotic twice daily for one week. In addition, patients advised to take systemic antibiotic therapy twice daily for one week.