Phase ?clinical trial of chicken type II collagen in rheumatoid arthritis

INTERVENTION: MTX group:MTX (10 mg/week) is applied in the treatment of ac;CII group:MTX (10 mg/week) is applied in the treatment of ac; CONDITION: Rheumatoid arthritis PRIMARY OUTCOME: Swollen joint count;Morning stiffness;health assessment questionnaire (HAQ);Tender joint count; SECONDARY OUTCOME: ESR;Rest pain;CRP; INCLUSION CRITERIA: RA patients aged from 18 to 65 years who met revised American College of Rheumatology (ACR) criteria for the diagnosis of RA were entered into the study after giving their written informed consent