Growth kinetics of Bu3 cells secreting HBsAg in microcarrier culture.

Authors
Category Primary study
JournalChinese journal of biotechnology
Year 1991
The genetically engineered mammalian cell (Bu3) secreting Hepatitis B surface antigen (HBsAg) was cultured on microcarriers semi-continuously. The growth model of Bu3 cells propagating on microcarriers, glucose consumption and lactate accumulation models were established. It is illustrated that the technology of anchorage-dependent Bu3 cell culture on microcarriers will give high yield and high HBsAg expression.
Epistemonikos ID: 4bfd2a464116a4f40f4c40ca8d56871a7bf234aa
First added on: Sep 20, 2024